Root Cause

The Three T’s in Action: Adrenals, Gut, and Your Body’s Toxic Load

By Dr. Karen West · August 2026

Part 2 of “Wellness Hacks for High-Achieving Women.” Part 1 redefined health as function, and named the three T’s — thoughts, traumas, toxins — that limit it. This part is about what the three T’s do to your adrenals, your gut, and your detox pathways — and where healing starts.

When stress runs the show

Chronic stress locks the body in fight-or-flight. In that state, digestion is inhibited, reproduction is inhibited, the liver dumps glucose for muscles you never use (hello, blood sugar spikes), heart rate and blood pressure climb, cortisol runs high — and the hormones you actually want, estrogen, progesterone, and testosterone, run low. Cholesterol often rises too, because the body makes stress hormones out of it.

Left long enough, this pattern has a familiar face:

  • Fatigue — the loss of youthful energy
  • Mood imbalances, including anxiety and depression
  • Brain fog
  • Hormone imbalances — adrenal, sex hormone, and thyroid
  • Weight-loss resistance or unexplained gain

How I approach healing the adrenals

Sleep hygiene first — nothing works without it. Then stress management (meditation is the best-studied), adaptogenic herbs, the right kind of exercise (more is not better here), vitamin C, and insulin management. Done patiently, mood, energy, cognition, and memory follow.

The gut: where the outside world becomes you

Your gut is influenced by antibiotic use, infections, genetics, diet and inflammation, sleep quality, environmental toxins, and stress. When it’s struggling, the signs go far beyond the stomach: heartburn and reflux, SIBO, IBS, joint aches, autoimmune flares, dermatitis, allergies, gas and bloating, headaches.

Where gut healing starts

  1. Digestion — restore the mechanics before anything fancy
  2. Inflammation — essential fatty acids and an elimination diet
  3. Microbiome — rebuild with pre- and probiotics together
  4. Immune support — secretory IgA, the gut’s first line of defense
  5. Nervous system — the vagus nerve, the cable between brain and gut

Remember: everything absorbed in the gut passes through the hepatic portal vein to the liver before it reaches the rest of you. Gut and liver are one conversation.

Toxins: the quiet third T

Eight signs your body’s toxic load may be outrunning its cleanup crew: excessive fatigue, allergies, stubborn weight gain, skin irritations, muscle aches, constipation, fluid retention, migraines.

Two facts I wish every parent knew: we absorb roughly 60% of what we put on our skin — and children absorb dramatically more. Over 100,000 chemicals circulate in the body-care industry, and less than 10% have been meaningfully tested for safety. Your liver clears what it can through its two-phase detoxification system, but the cheapest upgrade is reducing what goes on and in to begin with. Simplify the cabinets.

A story from my practice

A patient came to me on daily allergy pills, with puffy swollen eyes and three to four headaches a week. Allergy specialists had run inconclusive studies. Functional testing told a different story: her gut’s mucosal lining — the immune system’s first line of defense — was damaged. After twelve weeks of care focused on the gut, she had 90% improvement in allergy symptoms, 80% fewer headaches, and the most regular digestion of her life.

Nobody had asked about her gut, because the symptom said “allergies.” The root said otherwise.

The balance that holds it all up

Sleep hygiene. Clean, whole food. Exercise that energizes rather than depletes. Care for your spine — you only get one. Simplify your cabinets and pantry. Manage the stress you can’t eliminate. None of it is dramatic. All of it compounds.

Dr. Karen West, DC, FMACP — functional health educator, 15+ years in clinical practice, founder of West Health Spa, and mother of four raised on real food from day one. Full credentials →

A note from Dr. West: Everything I share here is education, drawn from my training, my years in practice, and my own family’s table. It is not medical advice for your specific situation, and it does not create a doctor-patient relationship. Talk with your physician before changing your health care.